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The emergency services are responding to an "ongoing emergency incident" in Liverpool city centre this evening.
A large cordon is in place around Queen Square bus station, with police officers, fire and rescue crews and paramedics in attendance. One vehicle appears to be behind a screen with emergency workers examining something at the scene.
A spokesman for Merseyside Police said he could not confirm the details of the incident but said it is an "ongoing emergency situation" and officers are "working to establish the circumstances".
Merseyside Fire and Rescue Service said the police are leading on the incident.
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Key Events
Hannah Rees
We're live from the scene
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KEY EVENT
Police statement in full
Merseyside Police have confirmed the incident involved two pedestrians being struck by a car.
This is the force's full statement:
"Officers remain on Queen Square in Liverpool after a collision this afternoon (Sunday 29 October).
At around 3.50pm we received a report of a collision involving a blue SEAT Ateca and two pedestrians near the bus station.
A man and a woman who sustained a serious head injury after the collision have both been taken to hospital for further treatment.
The driver of the car remained at the scene and is assisting officers with their enquiries.
The bus stop on Queen Square is closed whilst emergency services remain at the scene.
If you have any information on this incident DM @MerPolCC or Crimestoppers on 0800 555 111, quoting Log 660 of Sunday 29 October."
Jonathan Humphries
One side of station re-opened
One side of the bus station has re-opened, as frontline responders narrow their focus around the two vehicles by the Royal Court theatre
Jonathan Humphries
Car resting against Royal Court building
Images from the scene show a car which appears to have come to rest with its rear side against the Royal Court building. A black four-by-four is also within the cordon
Hannah Rees
'Serious RTC'
Update from Merseytravel.
Jonathan Humphries
'Huge cordon'
Police officers at the scene have cordoned off a large area around the scene of the incident
Hannah Rees
Latest update from Merseytravel
Queen Square Bus Station is closed inbound and outbound.
Jonathan Humphries
Pedestrians diverted through St John's
KEY EVENT
'Entire bus station behind cordon'
The ECHO's Dan Haygarth is at the scene.